Manufacturer: Bayer Health Care, West Haven, CT, and Onyx, Emeryville, CA Indication: Sorafenib tablets are indicated for the treatment of advanced renal cell carcinoma. Drug Class: As a multikinase inhibitor that targets a number of serine/threonine and receptor tyrosine kinases, sorafenib has the chemical name 4-(4-{3-[4-chloro-3-(tri-fluoromethyl)phenyl]ureido}phenoxy)-N2-methylpyridine-2-carboxamide 4-methylbenzenesulfonate.

Manufacturer: Pfizer, New York, NY Indication: Sunitinib (SU-11248) is a newly targeted anti-cancer therapy for patients with gastrointestinal stromal tumors (GISTs), a rare stomach cancer, who are intolerant of treatment with imatinib mesylate (Gleevec, Novartis). The capsules are also indicated for the treatment of advanced kidney cancer.

Cetuximab (Erbitux) Manufacturer: ImClone Systems, Inc., Branchburg, NJ, and Bristol-Myers Squibb, Princeton, NJ Indication: Cetuximab is indicated for use in combination with radiation therapy to treat patients with squamous cell cancer of the head and neck that cannot be removed by surgery. Cetuximab is also approved as monotherapy for patients whose head and neck cancer [...]