Sepsis syndrome consists of a collection of clinical manifestations of sepsis with evidence of organ dysfunction. In the early phase of sepsis, the tissues that usually become damaged and develop organ failure are the lungs. Pulmonary disorder may be followed by disorder of the liver and then the kidneys.

This study contained five different groups of animals. Survival rates at the 120th hour were 100% in groups SAG, SA and C. The rate was determined as 20% for group SG, and the mean duration of survival following inoculation was 14.25 ± 2.12 hours. In group S, all rats were dead by the end of [...]

The experiment was performed in adherence with the National Institutes of Health guidelines on the use of experimental animals. The study was approved by the university’s animal care committee. Fifty Sprague-Dawley rats (10 weeks old) weighing 200-250 g were allowed to become acclimatized to laboratory conditions for five days before experimental use. The animals were [...]

INTRODUCTION Sepsis is characterized by infection and a generalized systemic inflammatory response syndrome (SIRS), ultimately leading to multiple organ dysfunction syndrome (MODS) and death. During sepsis, the lungs are especially susceptible to damage, and a progressively impaired lung function is the first major complication in sepsis. Traditionally, strategies aiming at preventing or treating sepsis have [...]