LDH is an enzyme in the glycolytic pathway and its released as the result of cell damage. LDH isoenzyme analysis, which requires small volume samples, is quick and easy to perform. LDH isoenzymes may be useful in differential diagnosis since tissue damage releases isoenzymes contained therein, leading to a change in their pattern. Previous studies [...]

LDH levels and isoenzyme activities were studied in the ascitic fluid in malignant ascites and non-malignant ascites. Data regarding LDH and its isoenzymes of malignant and nonmalignant ascites were summarized in Table 1. LDH level and LDH isoenzyme activities of subgroups were shown in Table 2.

A total of 76 patients (43 males and 33 females) with ascites were investigated for their ascitic fluid LDH levels and its isoenzyme activities. Paracentesis were performed to all of the patients to highlight the underlying etiology of ascites. Biochemical, hematological and microbiological investigations were also performed. Complete blood count, biochemical examinations, ultrasonography and cytologic [...]

INTRODUCTION The lactate dehydrogenase (LDH) molecule is a tetramer composed of four polypeptide chains. There are five component isoenzymes as a result of the five different combinations that are produced by two polypeptide chains encoded by separate genes (M and H). LDH-1 is composed of four H subunits, and LDH-5 of four M subunits. The [...]