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Hepatitis C Virus/Human Immunodeficiency Virus Co-infection The coexistence of HCV and HIV poses a larger problem for the management of HCV. Because the modes of HIV and HCV transmission are similar, approximately 15% to 30% of HIV patients also become infected with HCV. Patients who have not used protease inhibitors (PIs) and those who consume [...]

The current gold standard for treatment of HCV is pegylated IFN alfa-2b combined with ribavirin generic for 48 weeks, depending on the genotype. However, more than 50% of patients do not respond completely to combination therapy, suggesting the need for more treatment options, such as ribavirin. The manufacturer recommends that patients weighing 75 kg or [...]

Although great strides have been made in the treatment of chronic HCV infection since the discovery of the virus in 1989, therapy remains problematic. Most patients with chronic infection (defined by the detection of HCV RNA for at least six months)45 have few signs and symptoms of disease. Infrequent signs and symptoms include fatigue, right [...]

First identified in 1988, HCV infection is caused by a small, single-stranded RNA virus that is a member of the genus Hepacivirus and the family Flaviviridae. HCV replicates in the cytoplasm of hepatocytes and B lymphocytes. Persistent infection or a lack of viral clearance is related to continuous virus production and to the loss of [...]

Introduction Identified more than a decade ago, hepatitis ะก virus (HCV) is the leading cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma (HCC) and is the primary indication for liver transplantation in the U.S. This common chronic blood-borne infection affects approximately 3.8 million people in the U.S., with more than 50% of these cases [...]

What is Hepatitis A – Hepatitis B – Hepatitis C: Hepatitis A – An inflammatory viral disease of the liver with a short incubation period. Hepatitis A may be transmitted by eating contaminated food, by fecal-oral contact, and/or through household contact. Hepatitis A may be mild to severe; symptoms include fever, nausea, and jaundice. Hepatitis [...]