Our study showed baseline differences among the non-hypertensive and hypertensive AAASPS enrollees. Specifically, the non-hypertensive African American enrollees were more likely to be current cigarette smokers and have higher education, and less likely to have old CT/MRI-based infarcts. On the other hand, hypertensive AAASPS enrollees, in addition to having htn, were more likely to have [...]

Demographic and Cardiovascular Factors (Table 1)
The mean age of hypertensive and non-hypertensive patients was 62.3 ± 10.4 and 59.1 ± 12.5 years (p=0.064), respectively. Women comprised 54% of the hypertensive and 41% of the non-hypertensive patients (p=0.030). The mean education of hypertensives was 11.1 ±3.1 compared to 11.7 ± 2.9 of non-hypertensives (p=0.024). A history [...]

MRI-based Infarcts and CT-based Infarcts
MRI and CT scans were reviewed by AAASPS local principal investigators and/or local radiolo gists for evidence, location and size of recent and old cerebral infarctions. MRI and CT results were classified according to TOAST criteria.

Demographics and Cardiovascular Factors
The database for this analysis was the AAASPS. AAASPS is an ongoing NIH-spon-sored, multi-center, randomized, double-blind clinical trial designed to compare the effect of ticlopidine and aspirin in the prevention of recurrent stroke, myocardial infarction, and vascular death in AAs with recent, noncardioembolic ischemic stroke. Eligibility criteria for the study have been [...]

African Americans (AAs) are at high risk of stroke and dying from stroke. Explanations for excess stroke risk among AAs include higher prevalence of cardiovascular risk factors, greater severity of risk factors or greater sensitivity to the risk factors, and lack of access to medical care. AAs have a disproportionate burden of many of the [...]