Hepatitis B Virus (HBV)

Tag: Cancer

Factors Associated with Fatal Hemoptysis in Cancer Patients: Conclusion

In patients with a primary bronchogenic tumor, fatal hemoptysis was frequently associated with a necrotic squamous cell carcinoma. Previously, investigators have shown an increased tendency in this cell type to cause tissue necrosis and subsequent hemorrhagic infarction. A proposed mechanism for the development of necrosis in squamous cell carcinoma is tumor invasion of vascular structures […]

Factors Associated with Fatal Hemoptysis in Cancer Patients: Outcome

Factors Associated with Fatal Hemoptysis in Cancer Patients: Outcome

Candida spp may also play a causative role in pulmonary hemorrhage as demonstrated by two patients with hemoptysis and a Candida pneumonia. One of these patients had a C tropicalis pneumonia and developed fatal hemoptysis, whereas the patient with a C albicans pneumonia experienced only selflimited hemoptysis. The increased virulence of C tropicalis has been […]

Factors Associated with Fatal Hemoptysis in Cancer Patients: Discussion

Unfortunately, diagnosis of fungal infections is difficult in immunocompromised patients. An antemor-tem diagnosis of fungal pneumonia was achieved in seven of eight patients in our study, but in two patients this diagnosis was made only from a sputum culture relatively late in the clinical course. Further, autopsies were not performed on all of our patients, […]

Factors Associated with Fatal Hemoptysis in Cancer Patients: Solid Tumors

Factors Associated with Fatal Hemoptysis in Cancer Patients: Solid Tumors

Solid Tumors The clinical characteristics of patients with fatal hemoptysis or nonfatal hemoptysis are presented in Table 3. The two groups contained similar proportions of patients with a bronchogenic carcinoma or a malignancy metastatic to the lung. Two patients with esophageal carcinoma and contiguous extension to the tracheobronchial tree had fatal hemoptysis. In patients with […]

Figure 1. Invasive pulmonary aspergillosis in patient l with leukemia and no bone marrow recovery A left': Thrombosis of a pulmonary artery by Aspergillus hvphae (arrwsj without inflammatory disruption of the vessel wall. Surrounding pulmonary parenchyma shows hemorrhagic infarction (hematoxylin and eosin stain, original magnification x 2.5). B (right): Invasion and disruption of a pulmonary artery wall by Aspergillus hyphae (arrows) without granulocytic inflammation (periodic acid-Schiff stain, original magnification, x230.)

Factors Associated with Fatal Hemoptysis in Cancer Patients: Results

Classification Patients were grouped by the type of neoplasm: hematologic malignancy or solid tumor. These groups were further subdivided by the severity of hemoptysis: fatal hemoptysis or nonfatal hemoptysis. Inadequate documentation of the quantity of hemoptysis in the medical records prevented further grading of the severity of hemoptysis. Statistical Analysis Differences in frequencies of various […]

Factors Associated with Fatal Hemoptysis in Cancer Patients

Factors Associated with Fatal Hemoptysis in Cancer Patients

Pulmonary hemorrhage occurs frequently in patients with neoplastic diseases and may become life-threatening in a significant proportion of these patients. The factors contributing to the development of fatal pulmonary hemorrhage in patients with malignant disease have not been well delineated. To address these issues, we reviewed the clinical records and available pathologic specimens from patients […]

Crohn’s disease

Anti -TNF therapy and malignancy – A critical review: CONCLUSIONS

We have provided an analysis of the association between anti-TNF-a therapy and a possible increase in solid tumour and lymphoma development. At this time the database remains relatively small. Furthermore, the studies were clearly not powered to detect any causal relationship between anti-TNF-a therapy and a relatively rare event such as cancer. Analysis of the […]

Tags