Persistence of Toluene Diisocyanate-Induced Asthma Despite Negligible Workplace Exposures
HPoluene diisocyanate is a low molecular weight chemical used primarily in the manufacture of flexible polyurethane foams. Workplace exposures to this agent can cause asthma. Among TDI workers, asthma caused by this agent has been reported to be relatively commonplace. A 1977 report showed workplace-induced asthma present in approximately 5 percent of TDI production workers.
On a practical level, when a worker is found to have TDI-induced asthma, the counselling physician is called on to assess whether the worker can remain in the workplace. One strategy, without the social and financial implications of discharging the worker and the legal implications to the company, is to move the sensitized worker from his usual workplace area to a part of the workplace recognized to have no or negligible TDI exposure. vardenafil 20 mg
In the course of an epidemiologic survey of the respiratory health of workers using TDI to produce polyurethane foam, we performed serial assessments of six workers with challenge test-proven TDI-induced asthma transferred within the workplace where TDI exposures were thought to be negligible or absent.