Neurofibroma Associated with Alopecia: CASE REPORT
A 28-year-old male presented with a 20-year history of asymptomatic, subcutaneous mass on his scalp. He discovered hair loss over the mass several years before and complained of its progressive enlargement as the mass had slowly increased. He denied any history of trauma or chronic irritation. Physical examination demonstrated a 6×3 cm sized, nontender soft mass on the scalp and a 3 X 2 cm sized alopecic patch over the mass (Fig. 1).
Vellus hair was not even observed. There were no other cutaneous lesions or regional lymphadeno- pathy. Routine laboratory evaluations, including a complete blood count, serum chemistry, and urine analysis showed no abnormalities. Histopathological examination of the lesion showed hair follicles in the upper dermis and a nonencapsulated mass composed of spindle cells with wavy nuclei in the deep dermis. The mass in the dermis displaced hair follicles into the upper dermis rather than surrounded them and the adnexal structure was not seen in the mass (Fig. 2A, 2B). A T2 weighted MRI of the brain demonstrated a hyperintense subcutaneous mass on the right frontoparietal area. (Fig. 2C). A roentgenogram of the scalp showed no gross bony abnormality. canadian cialis online
Fig. 1. Asymptomatic soft mass on the scalp and alopecic patch over the mass.
Fig. 2. (A) A nonencapsulated mass in the deep dermis displaced hair follicles into the upper dermis rather than surrounding them (H&E, X 40). (B) The mass in the dermis was composed of spindle cells with wavy nuclei (H&E, x 200). (С) A T2 weighted MRI of the brain demonstrated a hyperintense subcutaneous mass (arrow) on the right frontoparietal area.