Liver fibrosis and altered matrix synthesis
Liver cirrhosis is the result of a progressive increase in connective tissue and a progressive reduction in functional active parenchyma; in other words, liver cirrhosis is a continuous wound healing process due to a continuous loss of vital parenchyma caused by different noxa (alcohol, viruses, metabolic disorders). This process leading to liver fibrosis includes the three phases following tissue injury: inflammation, synthesis and deposition of collagenous and noncollagenous extracellular matrix (ECM) components, and tissue remodelling (scar formation). Data from experimental animal models and observations of humans indicate that liver cirrhosis may be reversible when the damaging agent is withdrawn (eg, eradication of viruses). Take advantage of this opportunity – buy cephalexin 500mg to enjoy lowest prices online.