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Category: Serotonin syndrome

Fatal serotonin syndrome. A report of two cases: DISCUSSION

The true incidence of the serotonin syndrome is unknown but was originally felt to be rare. There continues to be a need to develop diagnostic criteria and better recognition ofthis adverse drug event. Physicians will then be more able to recognize, treat, report and, better still, prevent potentially fatal drug in ter actions. The two […]

depressed

Fatal serotonin syndrome. A report of two cases: SEROTONIN SYNDROME

Serotonin syndrome was described by Insel et al in 1982. It appears to be dis-inct from malignant hyper-hermia and neu rolep tic ma lig nant syn drome. The in ter action of sero to -nergic agents and monoamine oxidase inhibi-ors is a commonly accepted etiology, although the exact pathophysiological mechanism has not been completely delineated. […]

Fatal serotonin syndrome. A report of two cases: CASE 2 PRESENTATION

The second case was a 24-year-old female who had suffered childhood abuse. She developed addiction problems with alcohol and street drugs, and de pres sion was a re cur rent theme. She had physical complaints as well and focused considerable attention on these. She had been treated by many psychiatrists and mental health workers. Several […]

Antidepressants1

Fatal serotonin syndrome. A report of two cases: CASE 1 PRESENTATION

The first case involved a 49-year-old female with an ex-ensive his-ory of recurring depressions for at least 20 years. Drug abuse of narcotics and alcohol led to her treatment at a major addiction centre on more than one occasion in the early 1980s. She had numerous family doctors, psychiatrists and other mental health care workers […]

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