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Category: Pulmonary Disease

Bilateral Carotid Body Resection for the Relief of Dyspnea in Severe Chronic Obstructive Pulmonary Disease: Conclusion

Although all three of our patients eventually died, it is difficult to assess whether or not their survival was shortened by BCBR. On direct questioning they stated that their improved comfort justified the possibility of decreased longevity from the operation. Depression of ventilation and worsening of blood gases clearly occurred in all. Although one might […]

Bilateral Carotid Body Resection for the Relief of Dyspnea in Severe Chronic Obstructive Pulmonary Disease: Outcome

Bilateral Carotid Body Resection for the Relief of Dyspnea in Severe Chronic Obstructive Pulmonary Disease: Outcome

The postoperative decrease in Vo2 and Vco2 during exercise probably reflects in part decreased work of breathing due to reduction in ventilation, as the patients were doing the same amount of external work. However, we cannot exclude the possibility that at least part of the decrease in Vo2 and Vco2 was related to a more […]

Bilateral Carotid Body Resection for the Relief of Dyspnea in Severe Chronic Obstructive Pulmonary Disease: Discussion

Dyspnea may be an incapacitating symptom in patients with COPD. Efforts to relieve it with standard modalities such as bronchodilators, corticosteroids, oxygen, physical retraining, respiratory muscle training, nutrition and even psychoactive drugs are frequently inadequate. Bilateral carotid body resection is an intriguing but unproven and potentially dangerous procedure for the relief of this symptom in […]

Figure 1. Changes in lung mechanics and volumes after bilateral carotid body resection were small and of no clinical importance.

Bilateral Carotid Body Resection for the Relief of Dyspnea in Severe Chronic Obstructive Pulmonary Disease: Results

Results All three patients had severe airflow limitation and hyperinflation which was not affected by the surgery (Fig 1). The moderate preoperative resting and exercise hypercapnea and hypoxemia deteriorated markedly postoperatively, though there was no change in the alveolar-arterial oxygen difference or pH (Table 1). Ventilation fell postoperatively both at rest ( — 25 percent) […]

Bilateral Carotid Body Resection for the Relief of Dyspnea in Severe Chronic Obstructive Pulmonary Disease: Materials and Methods

We studied three men who were 57, 67 and 69 years old at the time of initial presentation to our rehabilitation program. They had severe COPD (FEV, <0.75 L) related historically to cigarette smoking, and when first seen, could walk only short distances (<200 m) at slow paces (0.8-1.2 mph). All of them were on […]

Bilateral Carotid Body Resection for the Relief of Dyspnea in Severe Chronic Obstructive Pulmonary Disease

Bilateral Carotid Body Resection for the Relief of Dyspnea in Severe Chronic Obstructive Pulmonary Disease

Physiologic and Clinical Observations in Three Patients Dyspnea is the major limiting symptom of the chronic obstructive pulmonary diseases (COPD). While treatment with bronchodilators, corticosteroids, and antibiotics can improve symptoms and pulmonary function in some patients with COPD, dyspnea remains a severe symptom for many despite pulmonary rehabilitation with physical training, oxygen supplementation, inspiratory muscle […]

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