Category: Pulmonary Amyloidosis

Discussion
Amyloid deposition in the vascular wall is commonly seen in amyloidosis and is known to make vessels fragile. Amyloidosis has been reported to cause massive hemorrhage in the skin, urinary bladder, gastrointestinal tract, and central nervous system.* As for pulmonary amyloidosis, amyloid deposition in the vascular wall is well known in diffuse septal amyloidosis. Road et al reported a case of diffuse septal amyloidosis with massive hemoptysis caused by a ruptured pulmonary artery. Amyloid deposition in the vascular wall was regarded as having caused the rupture. In case of nodular amyloidosis, vascular deposition is also known, but few bleeding cases have been reported. read …Read the rest of this article

Pulmonary Amyloidosis with Pulmonary Arteriovenous FistulaAmyloid deposition has been reported to make vessels fragile, and some cases of hemorrhage caused by amyloidosis have been reported. We report herein a case of pulmonary amyloidosis suspected of causing a pulmonary AV fistula. read only
Case Report
A 77-year-old man was admitted for close examination of abnormal shadows on his chest roentgenogram, which was taken during a routine check-up. His medical history revealed a gastric ulcer and cerebral hemorrhage. His family history was unremarkable. At the age of 62, his chest roentgenogram showed two tumorous shadows in the left upper lobe, and an open biopsy disclosed “benign lung tumors” of unknown origin. Since then he had received no treatment or follow-up examination. On admission, he was asymptomatic and his physical examination disclosed bruit on the right chest wall audible only on inspiration. No telangiectasia was seen on his skin or in his oral cavity. Laboratory data revealed increased ESR, CRP and CEA. Blood gas analysis showed mild hypoxia (PaOs of 62 mm Hg, PaC02 of 33 mm Hg) while the results of a lung (unction test were unremarkable. Sputum examination did not suggest malignancy or tuberculosis. Chest roentgenogram revealed bilateral multiple nodular calcified shadows (Fig 1). …Read the rest of this article