TTigh airway pressure may have adverse effects on pulmonary parenchyma. Greenfield et al dem­onstrated that severe bilateral pulmonary atelectasis occurs when healthy dogs are mechanically ventilated for 2 h with peak airway pressures equal to 26 to 32 cm H20. Barsch and coworkers showed that longer exposure (22 to 70 h) to elevated airway pressures [...]

The percentage of lung with emphysema by CT “density mask” quantitation correlated inversely with indices of airflow FEV1 FEV./FVC (Fig 4), FEF50%, and with diffusing capacity, expressed both as Dsb percent predicted and as a Dsb/Ул ratio percent predicted. Our findings agree with those in a previ­ously reported study from our institution by Morrison and [...]

In this study we used the CT “density mask” program to quantitate areas with attenuation values less than —910 HU which were taken to represent areas of emphysema, and to provide an overall percentage of lung involvement by emphysema. The CT quantitation of emphysema was correlated with mean lung density, overall lung volume and with [...]

The CT “density mask” results for both lungs are summarized in Table 1, which shows mean lung density, total CT lung volume, total volume of emphy­sema, and percentage oflung with emphysema. There was good correlation between the mean lung density and each of the following: total CT lung volume, total CT volume of emphysema and [...]

We studied 85 patients, 52 males and 33 females, ranging in age from 40 to 78 years (mean age ± SD = 64 ± 8 yr). They were selected from patients tested in the Vancouver General Hospital Pulmonary Function Laboratory during investigation for suspected malignancy. Patients with tumors were included if the tumor was peripheral [...]

Emphysema is defined as “a condition of the lung  characterized by abnormal permanent enlarge­ment of the airspaces distal to the terminal bronchi­oles, accompanied by destruction of their walls, and without obvious fibrosis. Computed tomography has been shown to be a sensitive technique in evaluating the presence and severity of emphysema. On CT, emphysema is characterized [...]

The diagnosis of drug-induced pneumonitis is always difficult, and it may have justified the need for pulmonary biopsy. However, the histologic findings are rarely specific. In our patient, the variations of cellular data obtained by BAL after resumption of treatment with the drug are of diagnostic interest as it was found that lymphocytosis and inversion [...]