A 65-year-old man visited our hospital with a history of multiple palpable cervical lymph nodes for several months. The cervical lymph node biopsy was done and he was diagnosed as Non-Hodgkin’s lymphoma, diffuse large B-cell type, in November 2000. He was treated with combination chemo­therapy comprising 6 cycles of CHOP regimen (epirubicin, cyclophosphamide, vincristine and [...]

INTRODUCTION Chemotherapy-induced acral erythema (CIAE) is an uncommon toxic reaction to a number of dif­ferent chemotherapeutic agents. It is characterized by symmetrical, well-demarcated, painful erythema on the palms and soles which may progress to bullae formation and desquamation. The drugs most often involved in this eruption are fluorouracil, cytosine arabinoside and doxorubicin. CIAE with bullous [...]

Ossification of the skin occurs in various lesions. There are two major forms of cutaneous ossification. Primary cutaneous osteoma is a primary tumor without a preceding cutaneous lesion. And secon­dary ossification, that is secondary osteoma cutis, has preexisting lesions, such as pilomatricoma, basal cell carcinoma, acne, melanocytic nevi, cellular blue nevus, epidermal cyst, or malignant [...]

A 26-year-old Korean woman presented to our outpatient clinic who had suffered from a small asymptomatic pigmented nodule on the right of her forehead for several months. There was no evidence of Albright’s hereditary osteodystrophy or Gardner’s syndrome in either the patient or her family. On the physical examination, 0.5 x 0.5 cm sized, relatively [...]

INTRODUCTION Secondary cutaneous osteomas have been reported in various lesions, including acne, melanocytic nevi, cellular blue nevus, pilomatricoma, epidermoid cyst, basal cell carcinoma, squamous cell carcinoma, or malignant melanoma. Among these, melanocytic nevus associated with one or several foci of cutaneous ossification, is known as nevus of Nanta. In several large series of reports in [...]

Neurofibromas may occur as a solitary tumor or as multiple lesions in a segmental or widespread distribution, referred to as neurofibromatosis. Neuro­fibromas are complex proliferations of the various components of the neuromesenchyme, including Schwann cells, endoneurial fibroblasts, perineural cells, and mast cells. In this complex proliferation, however, the proportion of each cell type varies, pro­viding [...]

CASE REPORT A 28-year-old male presented with a 20-year history of asymptomatic, subcutaneous mass on his scalp. He discovered hair loss over the mass several years before and complained of its progressive enlargement as the mass had slowly increased. He denied any history of trauma or chronic irritation. Physical examination demonstrated a 6×3 cm sized, [...]