Hepatitis B Virus (HBV)

Category: Disease (Page 3)

Treatment of primary hypercalciuria: Recent issues on treatment of genetic hypercalciuria

The amazing advances in molecular genetics have also in­volved hypercalciuria, and at least three candidate genes were shown to arbour mutations leading to altered calcium excretion. The chloride channel 5 (ClC-5), the calcium sensing receptor and the paracellin-1 are proteins encoded by corresponding genes, whose mutations causing either loss or gain of function, lead to […]

Treatment of primary hypercalciuria

Introduction Idiopathic hypercalciuria is the most frequent metabolic abnor­mality since up to 40 to 60% of patients with nephrolithiasis are hypercalciuric. Fasting hypercalciuria, accompanies id­iopathic hypercalciuria in up to 50% of the patients. It is widely agreed that high calcium excretion may be causative for stone disease, because the higher calcium concentration, the higher the […]

Yellow Nails, Lymphedema and Pleural Effusion: DISCUSSION

Pleural effusions in the yellow nail syndrome are thought to be secondary to dysfunction of pleural lymphatics. Once present, they tend to persist and may recur rapidly after therapeutic thoracentesis, making this an impractical option in many symptomatic patients. Chemical pleurodesis using quinacrine (Atabrine) and tetracycline has been successful in two patients. Nine patients have […]

Excessive Daytime Sleepiness in Chronic Obstructive Pulmonary Disease: DISCUSSION

The data reported in this study do not support the notion of a strong relationship between hypoxemia per se and an objective measure of EDS in a group of patients with chronic daytime and nocturnal hypoxe­mia. Taken together, this group of patients with COPD did not reveal any evidence of subjective or objective EDS as […]

Excessive Daytime Sleepiness in Chronic Obstructive Pulmonary Disease: RESULTS

Table 1 presents a comparison of the age, weight, and waking respiratory measures. Overall (n=14), there was no significant correlation between mean sleep onset latencies on the MSLT and waking Pa02 (- .13), PaC02 (.02), FEV, (.04), or mean spontaneous desaturation during sleep (.31). The mean sleep onset latencies were well within the published normal […]

Excessive Daytime Sleepiness in Chronic Obstructive Pulmonary Disease: MATERIALS AND METHODS

Fourteen male patients with stable COPD were randomly se­lected from the Chest Medicine Clinic at the Veterans Administra­tion Medical Center in Oklahoma City. Patients were selected without regard to the presence or absence of daytime sleepiness. The mean age was 60 years (range, 48 to 72 years). Patients were selected with a waking Pa02 of […]

Excessive Daytime Sleepiness in Chronic Obstructive Pulmonary Disease

The common occurrence of excessive daytime sleepiness (EDS) in patients with obstructive sleep apnea remains perhaps the most enigmatic aspect of what has been called the obstructive sleep apnea syndrome (OSAS). Initial speculation related EDS to the most obvious cause, ie, sleep deprivation, since it had been noted that these patients have numerous arousals from […]