Atorvastatin calcium: DOSAGE(2)
In addition, analysis of pooled data from several studies involving over 2000 patients with mild to moderate hypercholesterolemia showed that over 70% of patients had at least a 30% reduction in LDL-C levels with the 10 mg/day dose and that 95% of patients achieved 15% or greater lowering of LDL-C with this dose (unpublished data, personal communication). The same analysis showed that at higher doses, 20 mg/day and 40 mg/ day, 87% to 92% of patients achieved a 30% or greater reduction in LDL-C level and that 70% of patients achieved a 40% or greater lowering of LDL-C level. These data further suggest that the majority of patients treated with atorvastatin may be maintained on the starting dose and may achieve desired cholesterol lowering levels. Higher doses may offer the utility of further reductions in patients who require a 40% or greater reduction in LDL-C. buy levaquin online
The LDL-C lowering efficacy of atorvastatin is not affected by the presence of food or by morning or evening administration . Plasma concentrations and LDL-C lowering efficacy of atorvastatin are similar in patients with moderate renal insufficiency and in those with normal renal function; therefore, dose adjustment is not necessary in these patients . However, as a precaution, the lowest dose should be used in patients with severe renal impairment.