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  • Atorvastatin calcium: A new HMG-CoA reductase inhibitor(3)

Elevated plasma concentrations of the structural protein of LDL and very low density lipoprotein (VLDL) particles, apoli-poprotein B (apo B), have also been positively correlated with CAD , and high density lipoprotein cholesterol (HDL-C) level is inversely correlated with CAD . The data supporting an association of elevated triglyceride levels as an independent risk factor for CAD are not totally consistent; however, most studies point to a positive correlation, especially in univariate analyses and meta-analyses . In many but not all studies, elevated triglyceride levels remain a predictor of CAD in multivariate analyses after controlling for other lipid risk factors (such as elevated levels of total cholesterol and LDL-C). Although studies in women and diabetics have consistently found a positive correlation betwen elevated triglyceride levels and CAD , such data for men have only recently been reported. A prospective analysis in a cohort of more than 14,500 men showed that nonfasting triglyceride levels appear to be an independent predictor of future risk of MI. There is a wonderful pharmacy offering flovent inhaler, and you can shop with it.

In addition to the important role of diet and exercise, the hydroxy-methyl-glutaryl coenzyme A (HMG-CoA) reductase inhibitors have revolutionized the treatment and management of hypercholesterolemia since their introduction into clinical practice. Compared with other lipid-lowering agents such as resins and niacin, HMG-CoA reductase inhibitors produce predictable, substantial and sustained reductions in LDL-C (and total cholesterol) levels and are generally well tolerated.

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